Does CBD oil react with antidepressants? CBD Can Alter the Effects of Antidepressants
Since CBD interferes with the enzymes in the liver that break down many drugs, including antidepressants, their interactions may lead to insufficient concentrations of the drug in the body — resulting in a subtherapeutic effect.
What medications should not be taken with CBD?
As examples, you may experience increased side effects if CBD is used along with these drugs:
- Antidepressants (such as fluoxetine, or Prozac)
- Medications that can cause drowsiness (antipsychotics, benzodiazepines)
- Macrolide antibiotics (erythromycin, clarithromycin)
- Heart medications (some calcium channel blockers)
Can I take SSRI and CBD oil? Accumulating data suggest that CBD and THC affect concentrations of CYP2C19-metabolized SSRIs, including es/citalopram and sertraline. Using cannabidiol and or THC likely increases sertraline and es/citalopram concentrations in adolescents and may increase the risk of concentration-related SSRI side effects.
Does CBD Oil interact with psychiatric medications? Therefore, CBD will most likely interfere with the serum levels of other medications such as antibiotics, antipsychotics, antidepressants and blood thinners as well as many more. Studies about these interactions are yet lacking.
Does CBD oil react with antidepressants? – Additional Questions
What is the downside of CBD oil?
Though it’s often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications you’re taking, such as blood thinners. Another cause for concern is the unreliability of the purity and dosage of CBD in products.
Can CBD make you feel more depressed?
There’s no clear evidence to suggest CBD could increase feelings of depression. But since fatigue is associated with depression, it’s important to be aware of that potential side effect. If you’d like to use CBD to treat depression, consider whether it could interact with medication you’re currently taking.
How does CBD oil affect serotonin levels?
CBD doesn’t necessarily boost serotonin levels, but it may affect how your brain’s chemical receptors respond to the serotonin that’s already in your system. A 2014 animal study found that CBD’s effect on these receptors in the brain produced both antidepressant and anti-anxiety effects.
Can CBD help with bipolar disorder?
There’s limited information on the effects of CBD in people with bipolar disorder. But available evidence doesn’t really support the idea that CBD can help with bipolar disorder. A 2020 review , for example, suggests that CBD may help reduce symptoms of mental health conditions like social anxiety and schizophrenia.
Can I take CBD with sertraline?
sertraline cannabidiol
Using sertraline together with cannabidiol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.